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.406 Ventures, venture capital

.406 Ventures investing team: Standing, from left, Graham Brooks, Greg Dracon, Liam Donohue, Payal Agrawal Divakaran, Kathryn Taylor Reddy and Kevin Wang. Kneeling, from left, Austin Kwoun and Rebecca Redfield. Missing from photo: Trip Hofer.Image Credits:.406 Ventures

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.406 Ventures , a Boston - based speculation firm investing in go-ahead - focus startup in healthcare , data point and AI , and cybersecurity , closed its fifth stock with $ 265 million in capital committal .

The firm was base by Liam Donohue , who was the founder of Boston venture business firm Arcadia Partners , and two other cooperator , including Maria Cirino , atomic number 27 - founder of the managed - security measures services company Guardent , and former Razorfish CFO Larry Begley .

The novel fund is support by a grouping of new and exist limited partners , including university endowments , foundations , pension plans and strategic investor . let in the new monetary fund , the 18 - twelvemonth - old firm has raised more than $ 1.4 billion across its five core fund and three opportunity funds .

It ’s been awhile since TechCrunch catch up with the business firm . Speaking recently with Donohue , he say .406 Ventures ’ focus has n’t change much during that time . The firm continues to invest in those same three industries and leverage theBoston tech ecosystem , though it does invest across the nation .

However , unlike some of the firm ’s premature store , Donohue is seeing more repeat founders coming back for Modern investment funds .

“ We wanted to be a partner so that a founder would come back to us for their next thing , ” Donohue told TechCrunch . “ In store one and two , we had a couple of repetition founding father . In the more recent funds , I ’m excited to see so many great repeat partners make out back that a third of the 4th fund was repetition founding father , and I ’d expect about the same in investment firm five . ”

Boston - base .406 Ventures Closes Its Third Fund with $ 217 Million

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Over the two decades , the house has put together a portfolio of 87 companies , many of which have exited or start public . Most of late those have include Iora Health , acquire by OneMedical in 2021 and now part of Amazon Health . behavioural health caller AbleTo is under Optum Health . Meanwhile , Carbon BlackandCloudHealth Technologiesare part of VMware while cybersecurity insurance troupe Corvus was acquired by traveler in 2023 .

.406 Ventures has already made investment funds in four caller from the new store , let in Portrait Analytics , the developer of a generative AI political program for investiture inquiry and dissertation universe . It will gift in more than 20 companies with the new investment trust , Donohue said .

When reckon at startups within the three vertical of healthcare , data and AI , and cybersecurity , the firm view a number of factors , like the plan for infrastructure , especially now that AI is everywhere . It also exploit into executive councils of over 100 C - rooms manipulator from Fortune 500 companies .

“ We take ourselves , ‘ What are the new technology that are either going to need to be protect or will enhance and deepen the scourge factors ? ’ Donohue said . “ We ’re always look forwards three to five years and previse where the vulnerabilities are going to be and then who is building the protections for this . ”

5 investors discuss Boston ’s resilient technical school ecosystem